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Best of the Day: from the 2014 European Society of Medical Oncology (ESMO) Congress - Melanoma

In this "Best of the Day" interview from ESMO 2014, Dr. Axel Grothey is joined by Dr. Caroline Robert to review the latest advances, clinical trial updates, and late-breaking news presented during this year's Melanoma sessions. Discussion highlights include: an overview of anti-PD-1/PD-L1 antibodies approved or in development; emerging therapies for BRAF V600E/K mutation-positive melanoma; and late-breaking updates on the Phase III Co-BRIM trial.
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Best of the Day: from the 2014 European Society of Medical Oncology (ESMO) Congress - Gastrointestinal Cancer

In this "Best of the Day" interview from ESMO 2014, Dr. Axel Grothey is joined by Dr. Florian Lordick to review the latest advances, clinical trial updates, and late-breaking news presented during this year's GI Malignancies sessions. Discussion highlights include: new and emerging therapies for gastric, pancreatic, and colorectal cancers; immunotherapy for gastrointestinal malignancies; and antiangiogenic agents for advanced gastrointestinal malignancies.
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Best of the Day: from the 2014 European Society of Medical Oncology (ESMO) Congress - Genitourinary Cancers

In this "Best of the Day" interview from ESMO 2014, Dr. Ramaswamy Govindan is joined by Dr. Cora Sternberg to review the latest advances, clinical trial updates, and late-breaking news presented during this year's Genitourinary Cancer sessions. Discussion highlights include: practice-changing results from the CHAARTED prostate cancer trial; updates on PREVAIL, COUGAR 302, and AFFIRM trials; and an update on androgen receptor splice variant AR-V7's status as a biomarker to predict resistance to androgen receptor targeting agents.
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Best of the Day: from the 2014 European Society of Medical Oncology (ESMO) Congress - Lung Cancer

In this "Best of the Day" interview from ESMO 2014, Dr. Axel Grothey is joined by Dr. Ramaswamy Govindan to review the latest advances, clinical trial updates, and late-breaking news presented during this year's Thoracic Oncology sessions. Discussion highlights include: new therapies on the horizon for ALK-positive lung cancer; updates on RADIANT and ALCHEMIST thoracic cancer trials; and updates on the molecular characterization of tumors.
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Expert Perspectives: US Focus on Myeloproliferative Neoplasms and Myelodysplastic Syndromes 2014

Filmed at the US Focus on Myeloproliferative Neoplasms and Myelodysplastic Syndromes 2014 meeting, this video discussion between Drs. Srdan Verstovsek, Ruben A. Mesa, Jason R. Gotlib, and Ramon V. Tiu outlines key learning points and summarizes take home messages from the presented content. This engaging conversational format provides expert perspectives on recent discoveries that have the potential to change the paradigm of how MPNs and MDS are diagnosed and treated, and enhance clinical outcomes and quality of life for patients with MPNs and MDS.
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Webcast: Optimizing Clinical Outcomes for Patients with Polycythemia Vera: A Satellite Symposium during Perspectives in MPN and MDS 2014

Polycythemia vera is the most common of the myeloproliferative neoplasms characterized by elevated hematocrit, splenomegaly and increased thrombotic risk. Together these conditions result in significant symptom burden and a reduced quality of life for these patients. The recent identification of genetic variants associated with polycythemia vera have enhanced methods for classification and diagnosis of disease, contributed to more robust risk stratification models and led to the identification of novel targeted therapies for treatment of disease and alleviation of symptom burden. As these advances have the potential to provide significant benefits to patient quality of life and clinical outcomes, clinical challenges pertaining to incorporation of these new methodologies and therapies into everyday clinical practice are coming to light. Therefore, it is imperative that healthcare professionals are kept current of new and emerging clinically relevant findings and how their utilization in the clinical setting can provide optimal care for patients with PV for the enhancement of quality of life and clinical outcomes.
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1 ACCME
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Webcast: Clinical Trial Opportunities in Squamous Cell Carcinoma of the Lung

Dr. Mark Socinski highlights the epidemiology and current treatment outcomes of squamous cell carcinoma lung cancer patients and specifically details the effectiveness of different standards of care and emerging novel strategies for patients with squamous histology. He also discusses ongoing clinical trials with potential for benefit in this subset of patients.
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Expert Perspectives: 2014 Mastering Clinical Challenges & Emerging Therapies in IBD

Filmed at the 2014 Mastering Clinical Challenges & Emerging Therapies in IBD meeting, this video discussion between Dr. David T. Rubin, MD and Dr. David A. Schwartz, MD outlines key learning points and summarizes take home messages from the presented content. This engaging conversational format provides expert perspectives on current issues in choosing and incorporating novel therapies into practice and strategies to optimize clinical outcomes of various therapeutic regimens.
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Webcast: The Potential of Novel Strategies and Individualizing Care in Squamous Cell Carcinoma of the Lung

Dr. Suresh Ramalingam discusses the novel therapies, including immunotherapeutic agents and PARP inhibitors, for lung cancer. He elaborates on the mechanisms of action of the emerging strategies, the latest clinical data with different classes of agents, and ongoing clinical trials. Finally, he describes the rationale for treatment with specific targeted agents based on molecular biomarker profiling in the squamous lung cancer MASTER protocol.
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Expert Perspectives: 2014 Great Debates & Updates in Thoracic Malignancies

Filmed at the 2014 Great Debates & Updates in Thoracic Malignancies meeting, this video discussion between Dr. Ramaswamy Govindan, MD and Dr. Roy S. Herbst, MD, PhD outlines key learning points and summarizes take home messages from the presented content. This engaging conversational format provides expert perspectives on current issues in choosing and incorporating novel therapies into practice and strategies to optimize clinical outcomes of various chemotherapeutic regimens.
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0.5 ACCME